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2024年12月27日发(作者：w3c战网平台)

专利内容由知识产权出版社提供

专利名称：CASPASE-3 SUBSTRATE COMPRISING

IMAGING AGENTS

发明人：GUILBERT, Benedicte,CHAMPION,

Sue,GIBSON, Alexander, Mark,RICKETTS,

Sally-Anne,AVORY, Michelle,ARBO, Bente, E.

申请号：GB2006000398

申请日：20060203

公开号：WO06/082434P1

公开日：20060810

摘要：The present invention relates to diagnostic imaging agents for in vivo imaging.

The imaging agents comprise a synthetic caspase-3 substrate peptide labelled with an

imaging moiety suitable for diagnostic imaging in vivo. The invention also provides

radiopharmaceutical compositions comprising the imaging agents, together with kits for

the preparation of the radiopharmaceuticals. Also described are non-radioactive

precursors suitable for the preparation of the imaging agents. The imaging agents are

useful for the diagnostic imaging and or therapy monitoring in vivo of various disease

states where caspase-3 is involved.

申请人：GUILBERT, Benedicte,CHAMPION, Sue,GIBSON, Alexander, Mark,RICKETTS,

Sally-Anne,AVORY, Michelle,ARBO, Bente, E.

地址：GB,GB,GB,GB,GB,GB,NO

国籍：GB,GB,GB,GB,GB,GB,NO

代理机构：CANNING, Lewis, Reuben

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